Two products, one platform: riboLASSO for ready-to-use rRNA depletion, LASSOflex for custom DNA or RNA capture.
Ultra-selective
No nonspecific adsorption and no contaminant carryover. Near-zero background by design.
High binding capacity
Up to 20X higher binding capacity than commercial microbeads.
Redesignable
Swap the catcher strand to change the target entirely. One platform for DNA and RNA. No new kit each time.
Radically low-cost
Lower cost than bead-based capture, with no enzyme or cold-chain overhead to factor in.
Multiplexable
Combine catcher strands in a single reaction to capture or deplete several targets at once. Panels scale naturally.
Highly shelf-stable
Stable for approximately 1 year at 4°C. No enzyme cold-chain to manage.
Optionally developed for antibodies and drug molecules on request.
Sequencing
Clean, low-bias libraries for RNA-seq and NGS workflows.
Omics
Transcriptomics, proteomics, and multi-omics sample prep.
Diagnostics
Multiplexed panels for diagnostic and clinical workflows.
Drug discovery
Clean target isolation for functional and interaction studies.
Antibody & protein research
Custom antibody and protein target isolation on request.
Pathogen surveillance
Targeted enrichment for viral and microbial sequencing panels.
Includes protocols and direct support from our team.
riboLASSO
Cleaner RNA-seq. Less bias.
Pre-configured, add your total RNA and run. Over 98% depletion efficiency, bead-free and enzyme-free, at less than half the price of other kits.
LASSOflex
One platform. Any target.
Ships with the polymer and crosslinker library for custom DNA or RNA capture. Need protein, antibody, or another target type? We can help.
A DNA-crosslinked polymer platform for ultra-selective biomolecule capture. Instead of magnetic beads, it uses a synthetic capture material that forms a separable pellet, isolating your target without a solid interface.
riboLASSO is a ready-to-use kit pre-configured for human rRNA depletion. LASSOflex is the configurable platform. You design your own catcher strand to target custom DNA or RNA instead.
LASSOflex is currently offered for custom DNA and RNA capture. Dedicated mRNA capture is under planning. For protein, antibody, or other target types, contact us to discuss a custom arrangement.
Guides: What is RNA capture? · RNA pull-down methods compared · cfDNA and ctDNA sample prep · Multiplexed capture panels for NGS